SCIENTISTS MAKE BREAKTHROUGH THAT COULD CURE ALZHEIMER DISEASE – British scientists have hailed a latest breakthrough as a turning point in finding a cure for Alzheimer’s disease after managing to stop brain cells dying in laboratory mice.
According to Professor Roger Morris, of King’s College London, this new discovery could mean the prospect of a new drug that would not only help Alzheimer sufferers but also be able to tackle other brain conditions such as Parkinson’s and Motor Neurone diseases.
Professor Morris did point out that this current discovery is still in its very early stages of development but emphasized that the latest results on lab mice showed, for the first time, clear evidence that a drug could be developed that would stop brain cells from dying.
“This finding, I suspect, will be judged by history as a turning point in the search for medicines to control and prevent Alzheimer’s disease.” Professor Roger Morris, of King’s College London
The cause of Alzheimer’s is a toxic protein that basically clogs up the brain with a sticky mass and for years scientists have been trying to find an appropriate drug that would break-up the protein but his new method tackles the problem from a totally different angle which scientists feel could be the answer they have been searching for.
The research report states that instead of attempting to develop a drug that breaks down the protein they started looking at how ‘mis-folded’ proteins worked and the damage it causes. Scientist noted that proteins needed folding in a certain way to work properly but in the case of Alzheimer’s the proteins mis-folded therefore creating a mass that simply clogs up the brain cell.
The research currently being made on lab mice revealed some interesting results in that scientists discovered that mis-shapen proteins do not in fact kill brain cells, rather the cells kill themselves in an attempt to protect themselves – basically they stop making new proteins of which is vital for their survival.
Tests on lab mice with new the drug clearly showed that brain cells once again started to produce protein, in effect simply switching themselves back on which literal stops Alzheimer’s dead in its tracks.
The Journal Science Translational Medicine reported the findings and noted that mice treated with the drug showed every sign of remaining symptom free whilst others that were not provided with the drug continued to deteriorate.
Scientists admitted that they are still some way off producing a publically available drug as currently treatment does have severe side effects – it is expected that an effective and safe drug might be available within the next 10 to 15 years.
More on this story… Daily Mail